The ISEM themes related to Marine Science and Technology cover fundamental and applied areas on different evolutionary time scales. We are interested in the implementation of organizational plans at the base of metazoans. We also study the mechanisms at the origin of morphological variation through skeletal development in present-day selacians. This group is also the subject of ecological studies on the evolution of phenotypic diversity and geographical and bathymetric distribution. At an intermediate temporal scale, we are using evolutionary genomics approaches to study the mechanisms that generate biodiversity, such as speciation, in several groups ranging from molluscs to bony fish. The contemporary scale is also studied to understand the spatial genetic structure of coastal and abyssal marine species and their adaptations to environmental variations. The impact of recent environmental changes is studied in various contexts such as human-induced hybridization, biological invasions, communicable cancer epidemics, and the study of stocks of species exploited by fisheries. Finally, we are developing genomic resources and research programs in aquaculture aimed in particular at improving disease resistance in shellfish and fish.